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There are a number of brain imaging techniques that allow researchers to literally see how the brain reacts metabolically to various types of stimulation. For the most part they are based on MRI testing, but go beyond standard MRI in that they show increased or decreased brain metabolism (and thus implied hyper or hypo function). Because they are a test of brain function they are called functional magnetic resonance imaging, or fMRI for short. For the sake of simplicity, we well say that increased activity seen in these tests (known as brain region activation) is seen when a brain region "lights-up" during the scan. The opposite known as brain deactivation can also be documented in using this technology. These tests become useful in unraveling complex disease processes like fibromyalgia because they can show which brain regions "light-up" which deactivate and how these brain responses compare in patient suffering from fibromyalgia and healthy patients used as controls. Since fibromyalgia is a chronic pain state, it only makes sense that a number of investigators scanned patents with fibromyalgia and used a painful stimulus to observe how the fibromyalgia brain responded to pain. They did the exact same tests on a group of patients without fibromyalgia so they could compare brain responses between patients diagnosed with fibromyalgia and those who did not have fibromyalgia. The results are interesting.
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